Caspase-3 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCaspase-3
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, rat, mouse (expected from sequence)
Isotypen/a
Formataffinity purified
Size0.05 mL
Concentrationn/a
ApplicationsImmunohistochemistry (IHC) Paraffin, Western Blot (WB)
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DescriptionRabbit anti caspase-3 antibody recognizes caspase-3 also known as cysteine protease CPP32. Caspase-3, as the name implies, is a member of the cysteine-aspartic acid protease (caspase) protein family.Caspase-3 is an effector caspase that is activated by both the intrinsic and extrinsic apoptosis pathways. Caspase-3 is cleaved from an inactive 32 kDa zymogen/pro-enzyme into p17 and p12 subunits by the activated initiator caspases 9 and 8 in apoptotic cells. These subunits dimerize to form the active caspase 3 protein that cleaves and activates caspase-6 and 2. Through the activation/cleavage of downstream caspases, caspase-3 plays an important role in mediating apoptosis signaling.
ImmunogenImmunogen: Recombinant human caspase-3
Other Names[Caspase-3], [CASP3; CASP3; CPP32; SCA-1; CPP32B; CPP32; CASP-3; CPP-32; SCA-1]
Gene, Accession #[CASP3], Gene ID: 836, NCBI: P42574.2, UniProt: P42574
Catalog #MBS225328
Price$375
Order / More InfoCaspase-3 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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