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Antigenic Specificity | Rho H |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Rho H Polyclonal Antibody detects endogenous levels of Rho H protein. The protein encoded by RHOH is a member of the Ras superfamily of guanosine triphosphate (GTP)-metabolizing enzymes. The encoded protein is expressed in hematopoietic cells, where it functions as a negative regulator of cell growth and survival. RHOH may be hypermutated or misexpressed in leukemias and lymphomas. Chromosomal translocations in non-Hodgkin's lymphoma occur between this locus and B-cell CLL/lymphoma 6 (BCL6) on chromosome 3, leading to the production of fusion transcripts. Alternative splicing in the 5' untranslated region results in multiple transcript variants that encode the same protein. |
Immunogen | Immunogen: Synthesized peptide derived from the C-terminal region of human Rho H at AA rangle: 110-190 |
Other Names | [Rabbit Rho H; ARHH; TTF; Rho-related GTP-binding protein RhoH; GTP-binding protein TTF; Translocation three four protein] |
Gene, Accession # | [RHOH], Gene ID: 399, NCBI: NP_004301.1, UniProt: Q15669 |
Catalog # | MBS9705755 |
Price | $130, $220, $325 |
Order / More Info | Rho H Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |