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Antigenic Specificity | Phospho-RPS6KA5-S376 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Serine/threonine-protein kinase that is required for the mitogen or stress-induced phosphorylation of the transcription factors CREB1 and ATF1 and for the regulation of the transcription factors RELA, STAT3 and ETV1/ER81, and that contributes to gene activation by histone phosphorylation and functions in the regulation of inflammatory genes (PubMed:11909979, PubMed:12569367, PubMed:12763138, PubMed:9687510, PubMed:18511904, PubMed:9873047). Phosphorylates CREB1 and ATF1 in response to mitogenic or stress stimuli such as UV-C irradiation, epidermal growth factor (EGF) and anisomycin (PubMed:11909979, PubMed:9873047). Plays an essential role in the control of RELA transcriptional activity in response to TNF and upon glucocorticoid, associates |
Immunogen | Immunogen: A synthetic phosphorylated peptide around S376 of human RPS6KA5 (NP 004746.2). |
Other Names | [MSK1; RLPK; MSPK1] |
Gene, Accession # | [RPS6KA5], Gene ID: 9252, NCBI: NP_004746.2, UniProt: O75582 |
Catalog # | MBS8550691 |
Price | $280 |
Order / More Info | Phospho-RPS6KA5-S376 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |