Edit |   |
---|---|
Antigenic Specificity | Human CD42b |
Clone | [MM2/174] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry; Immunohistochemistry (Frozen Sections); Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Human CD42b. CD42b, also known as gpIb, is a two-chain membrane glycoprotein that forms a noncovalent complex with gpIX (CD42a) on the surface of platelets and megakaryocytes. Binding of the gpIb/gpIX heterodimer to von Willebrand factor bound to exposed subendothelial surfaces is essential for platelet adhesion at sites of injury.1-6. |
Immunogen | n/a |
Other Names | n/a |
Gene, Accession # | n/a |
Catalog # | MBS674244 |
Price | $165 |
Order / More Info | Human CD42b Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Schlossman, S., L. Bloumsell, W. Gilks, J.M. Harlan, C. Kishimoto, J. Ritz, S. Shaw, R. Silverstein, T. Springer, T.F. Tedder, and R.F. Todd, eds. 1995. Leukocyte Typing V: White Cell Differentiation Antigens, Oxford University Press, Oxford.2. Barclay, A.N., M.H. Brown, S.K.A. Law, A.J. McKnight, M.G. Tomlinson, and P.A. van der Merwe, eds. 1997. The Leukocyte Antigens Facts Book, 2nd Edition, CD42a, b Section, Academic Press, New York, p. 235.3. Thorsen, L.I., G. Gaudernack, N. Hack, J.M. Wilkinson, F. Brosstad, N.O. Solum, and N. Crawford. 1988. Brit. J. Haematol. 68:67.4. Hornby, E.J., S. Brown, J.M. Wilkinson, C. Mattock, and K.S. Authi. 1991. Brit. J. Haematol. 79:277.5. Berndt, M.C., X.P. Du, and W.J. Booth. 1987. Biochemistry 27:633.6. Roth, G.J. 1992. Immunol. Today 13:100. |