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Antigenic Specificity | SPAK (STK39) (C-term), 386-415 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: rat) |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This SPAK (STK39) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 386-415 amino acids from the C-terminal region of human SPAK (STK39). STK39 is a serine/threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress. |
Immunogen | n/a |
Other Names | [STE20/SPS1-related proline-alanine-rich protein kinase; Ste-20-related kinase; DCHT; Serine/threonine-protein kinase 39; STK39; SPAK] |
Gene, Accession # | [STK39], Gene ID: 27347, NCBI: NP_037365.2, UniProt: Q9UEW8 |
Catalog # | MBS9213434 |
Price | $165, $370 |
Order / More Info | SPAK (STK39) (C-term), 386-415 Antibody from MYBIOSOURCE INC. |
Product Specific References | Dowd, B.F., et al., J. Biol. Chem. 278(30):27347-27353 (2003). Johnston, A.M., et al., Oncogene 19(37):4290-4297 (2000). |