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Antigenic Specificity | CD3 epsilon |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | In immunology, the CD3 (cluster of differentiation 3) T-cell co-receptor is a protein complex and is composed of four distinct chains. In mammals, the complex contains a CD3gamma chain, a CD3delta chain, and two CD3epsilon chains. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. CD3 epsilon, also known as CD3E is a polypeptide which in humans is encoded by the CD3E gene which resides on chromosome 11.[1][2] It plays an essential role in T-cell development. |
Immunogen | Immunogen: A synthetic peptide (conjugated with KLH) corresponding to the N-terminal of human CD3 epsilon. |
Other Names | [CD3 epsilon], [CD3E; CD3E] |
Gene, Accession # | [CD3 epsilon], Gene ID: 442981, NCBI: AAA30834.1, UniProt: P27597 |
Catalog # | MBS355170 |
Price | $275 |
Order / More Info | CD3 epsilon Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Gold DP, Puck JM, Pettey CL, Cho M, Coligan J, Woody JN, Terhorst C (1986). Isolation of cDNA clones encoding the 20K non-glycosylated polypeptide chain of the human T-cell receptor/T3 complex. Nature 321 (6068): 431-4. 2. Clevers HC, Dunlap S, Wileman TE, Terhorst C (November 1988). Human CD3-epsilon gene contains three miniexons and is transcribed from a non-TATA promoter. Proc. Natl. Acad. Sci. U.S.A. 85 (21): 8156-60 |