RAB5A Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityRAB5A
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
FormatProtein G purified
Size0.05 mg, 0.1 mg
Concentrationn/a
ApplicationsELISA (EIA), Western Blot (WB), Immunofluorescence (IF)
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DescriptionThe small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes (PubMed: 10818110, PubMed: 14617813, PubMed: 16410077, PubMed: 15378032). Contributes to the regulation of filopodia extension (PubMed: 14978216). Required for the exosomal release of SDCBP, CD63, PDCD6IP and syndecan (PubMed: 22660413). Regulates maturation of apoptotic cell-containing phagosome
ImmunogenImmunogen: Recombinant Human Ras-related protein Rab-5A protein (1-215AA)
Other Names[Ras-related protein Rab-5A; RAB5A; RAB5]
Gene, Accession #[RAB5A], Gene ID: 5868, NCBI: NP_001278977.1, UniProt: P20339
Catalog #MBS7048980
Price$160, $235
Order / More InfoRAB5A Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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