Edit |   |
---|---|
Antigenic Specificity | HIF-1beta |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: HIF-1beta Polyclonal Antibody detects endogenous levels of HIF-1beta protein. ARNT encodes aryl hydrocarbon receptor nuclear translocator containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. Aryl hydrocarbon receptor nuclear translocator binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. Aryl hydrocarbon receptor nuclear translocator is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias. Alternative |
Immunogen | Immunogen: Synthesized peptide derived from the N-terminal region of human HIF-1beta at AA range: 1-80 |
Other Names | [Rabbit HIF-1beta; ARNT; BHLHE2; Aryl hydrocarbon receptor nuclear translocator; ARNT protein; Class E basic helix-loop-helix protein 2; bHLHe2; Dioxin receptor; nuclear translocator; Hypoxia-inducible factor 1-beta; HIF-1-beta; HIF1-beta] |
Gene, Accession # | [HIF-1beta], Gene ID: 405, NCBI: NP_001184254.1, UniProt: P27540 |
Catalog # | MBS9702217 |
Price | $130, $220, $325 |
Order / More Info | HIF-1beta Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |