Mouse CD178 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Mouse CD178 |
| Clone | [MFL4] |
| Host Species | Hamster |
| Reactive Species | n/a |
| Isotype | IgG |
| Format | fluorescein (FITC) conjugate |
| Size | 0.1 mg |
| Concentration | IgG concentration 0.1mg/ml |
| Applications | Flow cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Hamster anti Mouse CD178 antibody, clone MFL4 recognizes both mouse and rat CD178, otherwise known as Fas Ligand/ CD95L, a 40kDa type II transmembrane glycoprotein and member of the TNF/NGF superfamily, expressed by activated T cells and NK cells, which can be induced on a variety of cells by radiation, heat shock, chemotherapeutic agents and viral infection. CD178 acts as a key effector of cytotoxicity and in the regulation of immune responses. The binding of CD178 to its receptor CD95 (Fas), induces Fas-mediated apoptosis of target cells, and may be involved in the induction of peripheral tolerance and neutrophil chemotaxis. The binding of decoy receptor 3 (DcR3) to CD178 has been shown to inhibit CD178-mediated apoptosis. Hamster anti Mo |
| Immunogen | Immunogen: B6 mouse FasL/BHK cells Buffer Solution: Phosphate buffered saline Target Species: Mouse |
| Other Names | [tumor necrosis factor ligand superfamily member 6 isoform 1; Tumor necrosis factor ligand superfamily member 6; tumor necrosis factor ligand superfamily member 6; CD95 ligand; Fas antigen ligand; generalized lymphoproliferative disease; Fas ligand (TNF superfamily, member 6); CD95 ligand; CD95-L; Fas antigen ligand; Fas ligand; FasL; CD_antigen: CD178Cleaved into the following 4 chains:Tumor necrosis factor ligand superfamily member 6, membrane form; Tumor necrosis factor ligand superfamily member 6, soluble formAlternative name(s):Receptor-binding FasL ectodomain; Soluble Fas ligand; sFasL], [Fasl; Faslg; gld; CD178; CD95L; Fas-L; Faslg; CD95-L; Tnfsf6; APT1LG1; Apt1lg1; Cd95l; Fasl; gld; Tnfsf6; CD95-L; Fas ligand; FasL; sFasL; APL; FasL ICD; SPA] |
| Gene, Accession # | [CD178], Gene ID: 14103, NCBI: NP_034307.1, UniProt: P41047 |
| Catalog # | MBS219358 |
| Price | $370 |
| Order / More Info | Mouse CD178 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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