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Antigenic Specificity | p53 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG1 kappa |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Immunoblot, Immunoflourescence, Immunohistochemistry, Immunoprecipitation |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Anti-p53 [Murine MAb recognizes p53, a tumor suppressor gene product that is mutated in a wide variety of cancers. Epitope is in aa 14-389 of human p53.]. This antibody recognizes human p53, a tumor suppressor protein that is mutated in a wide variety of cancers. p53 is a nuclear protein that mediates cell cycle arrest in response to DNA damage which is important in maintaining genomic stability. |
Immunogen | Antigen: Beta galactosidase fusionprotein corresponding to aa 14-389 ofhuman p53. |
Other Names | [p53; p53], [TP53; TP53; P53; LFS1; TRP53; FLJ92943; P53] |
Gene, Accession # | Gene ID: 7157, NCBI: BAC16799.1, UniProt: P04637 |
Catalog # | MBS190360 |
Price | $425 |
Order / More Info | p53 Antibody from MYBIOSOURCE INC. |
Product Specific References | Iggo R et al. 1990. Lancet 335: 675-679; Gannon JV et al. 1990. EMBO 9:1595-1602; Said JW et al. 1992. AmerJ Path 141: 1343-1348; Bartek J et al.1991. Oncogene 6: 1699-1703. |