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Antigenic Specificity | SOX-2 |
Clone | [IHC665] |
Host Species | Mouse |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mL (Concentrate), 7 mL (Prediluted), 1 mL (Concentrate) |
Concentration | n/a |
Applications | n/a |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | SOX 2, also known as SRY (sex determining region Y)-box 2, is a transcription factor that acts to regulate pluripotency of undifferentiated embryonic stem cells, and to regulate gene expression in the stomach. This diagnostic grade SOX 2 IVD antibody is used to detect melanoma, testicular germ cell tumor, cervical carcinoma, lung cancer, breast cancer with basal cell phenotype, and teratoma of the central nervous system. SOX 2 has been reported as a predictor of poor outcome in stage I lung adenocarcinomas. Anti-SOX 2 is also used to recognize squamous cell carcinomas of the lung and gastrointestinal tract, and may be useful for detecting embryonal carcinoma. |
Immunogen | n/a |
Other Names | [SOX 2], [SOX2; SOX2; ANOP3; MCOPS3] |
Gene, Accession # | [SOX-2], Gene ID: 6657, NCBI: CAA83435.1, UniProt: P48431 |
Catalog # | MBS344080 |
Price | $170, $225, $300 |
Order / More Info | SOX-2 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Rizzino A, et al. Wiley Interdiscip Rev Syst Biol Med. 2009; 1:228-36.2. Laga AC, et al. Am J Pathol. 2010; 176:903-13.3. Ji J, et al. Hum Pathol. 2010; 41:1438-47.4. Rodriguez-Pinilla SM, et al. Mod Pathol. 2007; 20:474-81.5. Long KB, et al. Hum Pathol. 2009; 40:1768-73.6. Sholl LM, et al. Appl Immunohistochem Mol Morphol. 2010; 18:55-61.7. Tsuta K, et al. J Thorac Oncol. 2011; 6:1190-9.8. Gopalan A, et al. Mod Pathol. 2009; 22:1066-74. |