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Antigenic Specificity | LCK |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Lck Polyclonal Antibody detects endogenous levels of Lck protein. LCK is a member of the Src family of protein tyrosine kinases (PTKs). Tyrosine-protein kinase Lck is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants, encoding the same protein, have been described. |
Immunogen | Immunogen: Synthesized peptide derived from human Lck around the non-phosphorylation site of S540 |
Other Names | [Rabbit Lck; Tyrosine-protein kinase Lck; Leukocyte C-terminal Src kinase; LSK; Lymphocyte cell-specific protein-tyrosine kinase; Protein YT16; Proto-oncogene Lck; T cell-specific protein-tyrosine kinase; p56-LCK] |
Gene, Accession # | [LCK], Gene ID: 3932, NCBI: NP_001036236.1, UniProt: P06239 |
Catalog # | MBS9702400 |
Price | $130, $220, $325 |
Order / More Info | LCK Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |