Human NKp30 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman NKp30
Clone[9D31]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2
Formatunconjugated
Size0.1 mg
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS)
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DescriptionNKp30/NCR3, NKp44/NCR2, and NKp46/NCR1 are termed natural cytotoxicity receptors (NCR). These receptors are type I transmembrane proteins with 1-2 extracellular immunoglobulin domains, a transmembrane domain containing a positively charged amino acid residue, and a short cytoplasmic tail. All are expressed almost exclusively by NK cells and play a major role in triggering NK-mediated killing of most tumor cell lines. NKp44 is induced upon activation of resting NK cells with IL-2 and can bind to viral hemagglutinins. NK-mediated dendritic cell (DC) recognition is highly dependent on engagement of NKp30 and may result in lysis of the DC.
ImmunogenAntibody Generation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with extracellular domain of human recombinant protein of NKp30. The IgG2 fraction of the tissue culture supernatant was purified by Protein G affinity chromatography.
Other Names[NCR3; 1C7; MALS; CD337; LY117; NKp30], [NCR3; NCR3; 1C7; MALS; CD337; LY117; NKp30; 1C7; LY117; NK-p30; NKp30]
Gene, Accession #[NKp30], Gene ID: 259197, NCBI: NP_001138938.1, UniProt: O14931
Catalog #MBS690677
Price$490
Order / More InfoHuman NKp30 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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