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Antigenic Specificity | Human NKp30 |
Clone | [9D31] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2 |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | NKp30/NCR3, NKp44/NCR2, and NKp46/NCR1 are termed natural cytotoxicity receptors (NCR). These receptors are type I transmembrane proteins with 1-2 extracellular immunoglobulin domains, a transmembrane domain containing a positively charged amino acid residue, and a short cytoplasmic tail. All are expressed almost exclusively by NK cells and play a major role in triggering NK-mediated killing of most tumor cell lines. NKp44 is induced upon activation of resting NK cells with IL-2 and can bind to viral hemagglutinins. NK-mediated dendritic cell (DC) recognition is highly dependent on engagement of NKp30 and may result in lysis of the DC. |
Immunogen | Antibody Generation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with extracellular domain of human recombinant protein of NKp30. The IgG2 fraction of the tissue culture supernatant was purified by Protein G affinity chromatography. |
Other Names | [NCR3; 1C7; MALS; CD337; LY117; NKp30], [NCR3; NCR3; 1C7; MALS; CD337; LY117; NKp30; 1C7; LY117; NK-p30; NKp30] |
Gene, Accession # | [NKp30], Gene ID: 259197, NCBI: NP_001138938.1, UniProt: O14931 |
Catalog # | MBS690677 |
Price | $490 |
Order / More Info | Human NKp30 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |