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Antigenic Specificity | Prnp - middle region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, goat, human, rat, sheep |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against Prnp. It was validated on Western BlotTarget Description: Prnp may play a role in neuronal development and synaptic plasticity, may be required for neuronal myelin sheath maintenance and may play a role in iron uptake and iron homeostasis. Prnp is a soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. It also provides Cu2+ or ZN2+ for the ascorbate-mediated GPC1 deaminase degradation of its heparan sulfate side chains. |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Mouse Prnp |
Other Names | [major prion protein; Major prion protein; PrP27-30; PrP33-35C; CD_antigen: CD230] |
Gene, Accession # | [PRNP], Gene ID: 19122, NCBI: NP_035300, UniProt: P04925 |
Catalog # | MBS3215911 |
Price | $335 |
Order / More Info | Prnp - middle region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |