TNIK (Phospho-Ser764) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTNIK (Phospho-Ser764)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
FormatProtein A purified
Size0.1 mL
Concentration1mg/ml
ApplicationsImmunohistochemistry (IHC)-Paraffin, Immunofluorescence (IF)
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DescriptionSerine/threonine kinase that acts as an essential activator of the Wnt signaling pathway. Recruited to promoters of Wnt target genes and required to activate their expression. May act by phosphorylating TCF4/TCF7L2. Appears to act upstream of the JUN N-terminal pathway. May play a role in the response to environmental stress. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it may play a role in cytoskeletal rearrangements and regulate cell spreading. Phosphorylates SMAD1 on Thr-322.
ImmunogenImmunogen Type: Peptide-KLH Immunogen Description: KLH conjugated synthetic phosphopeptide derived from human TNIK around the phosphorylation site of Ser764
Other Names[TRAF2 and NCK-interacting protein kinase; TNIK; KIAA0551]
Gene, Accession #[TNIK], Gene ID: 23043, UniProt: Q9UKE5
Catalog #MBS9428990
Price$440
Order / More InfoTNIK (Phospho-Ser764) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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