ULK3 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | ULK3 |
| Clone | polyclonal |
| Host Species | n/a |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Description: Rabbit IgG polyclonal antibody for Serine/threonine-protein kinase ULK3(ULK3) detection. Tested with WB, IHC-P in Human;Mouse;Rat. Background: Serine/threonine protein kinase that acts as a regulator of Sonic hedgehog (SHH) signaling and autophagy. In search of potential homologues to Drosophila and human Fu, people have cloned human serine/threonine kinase ULK3 and assessed its ability to regulate GLI transcription factors, mediators of SHH signaling. And ULK3 enhances endogenous and over-expressed GLI1 and GLI2 transcriptional activity in cultured cells, as assessed by GLI-luciferase reporter assay. Besides that, ULK3 alters subcellular localization of GLI1, as assessed by immunofluorescent staining and immunoblotting assays. |
| Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at C-terminus of human ULK3 (427-454aa HTEVQNLMARAEYLKEQVKMRESRWEAD), different from the related mouse and rat sequences by four amino acids. Ig Type: Rabbit IgG |
| Other Names | [Serine/threonine-protein kinase ULK3; DKFZP434C131; FLJ90566; Serine/threonine-protein kinase ULK3; Ulk3; ULK3_HUMAN; unc 51 like kinase 3 (C. elegans); Unc-51-like kinase 3; unc-51 like kinase 3], [ULK3; ULK3] |
| Gene, Accession # | [ULK3], Gene ID: 25989, NCBI: NP_001092906.3, UniProt: Q6PHR2 |
| Catalog # | MBS177781 |
| Price | $315 |
| Order / More Info | ULK3 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Maloverjan A; Piirsoo M; Michelson P; Kogerman P; Osterlund T. Identification of a novel serine/threonine kinase ULK3 as a positive regulator of Hedgehog pathway. Exp Cell Res, 2010 Feb 15. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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