Phospho-CDC25B (Ser353) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Phospho-CDC25B (Ser353) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Phospho-CDC25B (Ser353) antibody detects endogenous levels of CDC25B only when phosphorylated at Serine 353. Description: CDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals.Function: Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Required for G2/M phases of the cell cycle progression and abscission during cytokinesis in a ECT2-dependent manner. Directly dephosphorylates CDK1 and stimulates its kinase activity. The three isoforms seem to |
| Immunogen | Immunogen: A synthesized peptide derived from human CDC25B around the phosphorylation site of Serine 353 Subcellular Location: Cytoplasm, Cytoskeleton, Microtubule Organizing Center, Centrosome. Cytoplasm, Cytoskeleton, Spindle Pole. Predicted Cross Reactivity: Bovine, Horse, Sheep Similarity: Bovine (86%), Horse (100%), Sheep (86%) |
| Other Names | [AI604853; Cdc 25B; Cdc25b; CDC25HU2; Cdc25m2; Cell division cycle 25 homolog B; Cell division cycle 25B; Cell division cycle 25B isoform 1; Cell division cycle 25B isoform 2; Cell division cycle 25B isoform 3; Cell division cycle 25B isoform 4; Cell division cycle 25B isoform 5; Dual specificity phosphatase Cdc25B; EC 3.1.3.48; M phase inducer phosphatase 2; M-phase inducer phosphatase 2; MPIP2_HUMAN] |
| Gene, Accession # | [CDC25B], Gene ID: 994, NCBI: NP_001274448.1, UniProt: P30305 |
| Catalog # | MBS9601028 |
| Price | $240, $280 |
| Order / More Info | Phospho-CDC25B (Ser353) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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