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Antigenic Specificity | RB1 (C-term), 858-886 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: rat) |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This RB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 858-886 amino acids from the C-terminal region of human RB1. RB1 is a negative regulator of the cell cycle and was the first tumor suppressor gene found. This protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. |
Immunogen | n/a |
Other Names | [Retinoblastoma-associated protein; p105-Rb; pRb; Rb; pp110; RB1] |
Gene, Accession # | [RB1], Gene ID: 5925, NCBI: NP_000312.2, UniProt: P06400 |
Catalog # | MBS9214609 |
Price | $165, $370 |
Order / More Info | RB1 (C-term), 858-886 Antibody from MYBIOSOURCE INC. |
Product Specific References | Connell-Crowley,L., et.al., Mol. Biol. Cell 8 (2), 287-301 (1997) Kitagawa,M., et.al., EMBO J. 15 (24), 7060-7069 (1996) |