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Antigenic Specificity | RHOC |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: RHOC antibody detects endogenous levels of total RHOC. Description: Rho family small GTPases, including Rho, Rac and cdc42, act as molecular switches, regulating processes such as cell migration, adhesion, proliferation and differentiation. They are activated by guanine nucleotide exchange factors (GEFs), which catalyze the exchange of bound GDP for GTP, and inhibited by GTPase activating proteins (GAPs), which catalyze the hydrolysis of GTP to GDP. A third level of regulation is provided by the stoichiometric binding of Rho GDP dissociation inhibitor (RhoGDI) (1). RhoA, RhoB and RhoC are highly homologous, but appear to have divergent biological functions. Carboxy-terminal modifications and differences in subcellular localizat |
Immunogen | Immunogen: A synthesized peptide derived from human RHOC Subcellular Location: Cell Membrane Predicted Cross Reactivity: Pig, Bovine, Horse, Dog, Chicken Similarity: Pig (100%), Bovine (100%), Horse (100%), Dog (100%), Chicken (89%) |
Other Names | [ARH12; ARHA; H12; ras homolog gene family member A; ras homolog gene family member B; ras homolog gene family member C; Rho cDNA clone 12; RHO12; RHOA; RHOA_HUMAN; rhob; rhoc; RHOH12; Small GTP binding protein RhoA; Transforming protein RhoA] |
Gene, Accession # | [RHOC], Gene ID: 389, NCBI: NP_001036143.1, UniProt: P08134 |
Catalog # | MBS9606866 |
Price | $240, $280 |
Order / More Info | RHOC Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |