Phospho-ATM (S1981) Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | Phospho-ATM (S1981) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Immunofluorescence (IF), Dot Blot (DB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This Phospho-ATM-pS1981 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S1981 of human ATM. ATM belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2,checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. ATM and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in the gene encoding AT |
| Immunogen | n/a |
| Other Names | [Serine-protein kinase ATM; Ataxia telangiectasia mutated; A-T mutated; ATM] |
| Gene, Accession # | [ATM], Gene ID: 472, NCBI: NP_000042.3, UniProt: Q13315 |
| Catalog # | MBS9202838 |
| Price | $165, $370 |
| Order / More Info | Phospho-ATM (S1981) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Brunet,J.,Clin. Genet. 73 (5), 465-473 (2008) Tsai,W.B., Nat. Cell Biol. 10 (4), 460-467 (2008) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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