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Antigenic Specificity | ATG4D |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | Protein G purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Immunofluorescence (IF), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Cysteine protease ATG4D: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms. |
Immunogen | Immunogen: This ATG4D monoclonal antibody is generated from mouse immunized with ATG4D recombinant protein. |
Other Names | [APG4D; AUTL4; APG4-D] |
Gene, Accession # | [ATG4D], Gene ID: 84971, NCBI: NP_116274.3, UniProt: Q86TL0 |
Catalog # | MBS8558597 |
Price | $280 |
Order / More Info | ATG4D Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |