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Antigenic Specificity | Human CD197/CCR7 |
Clone | [G043H7] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a, kappa |
Format | PE-Cy5 conjugate |
Size | 20 tests, 50 tests, 100 tests |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CCR7, also known as CD197, is a chemokine receptor that binds CCL19 and CCL21. CCR7 and its ligands link innate and adaptive immunity by affecting interactions between T cells and dendritic cells and their downstream effect. Naive T cells enter the lymph node through high endothelial venules, which express CCL21. Dendritic cells and macrophages enter the lymph node through afferent lymphatics. The encounter of T cells and dendritic cells in the T cell zone is CCR7-dependent. In addition, during immunological surveillance, B cells recirculate between B-cell-rich compartments (follicles or B cell zones) in secondary lymphoid organs, surveying for antigen. After antigen binding, B cells move to the boundary of B and T zones to interact with T- |
Immunogen | n/a |
Other Names | [CMKBR7; EBI1; EVI1; CCR-7; CDw197] |
Gene, Accession # | [CD197/CCR7], Gene ID: 1236, NCBI: NP_001829.1, UniProt: P32248 |
Catalog # | MBS2559148 |
Price | $125, $160, $210 |
Order / More Info | Human CD197/CCR7 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |