KDM1A Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-KDM1A antibody, protein, ELISA kits.
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|---|---|
| Antigenic Specificity | KDM1A |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Lysine-specific demethylase 1 (LSD1; also known as AOF2 and BHC110) is a nuclear amine oxidase homolog that acts as a histone demethylase and transcription cofactor (1). Gene activation and repression is specifically regulated by the methylation state of distinct histone protein lysine residues. For example, methylation of histone H3 at Lys4 facilitates transcriptional activation by coordinating the recruitment of BPTF, a component of the NURF chromatin remodeling complex, and WDR5, a component of multiple histone methyltransferase complexes (2, 3). In contrast, methylation of histone H3 at Lys9 facilitates transcriptional repression by recruiting HP1 (4, 5). LSD1 is a component of the CoREST transcriptional co-repressor complex that also c |
| Immunogen | Immunogen: Recombinant protein of human KDM1A Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Other Names | [KDM1; AOF2; BHC110; KIAA0601; LSD1; KDM1A] |
| Gene, Accession # | [KDM1A], Gene ID: 23028, NCBI: NP_001009999.1, UniProt: O60341 |
| Catalog # | MBS8502059 |
| Price | $310 |
| Order / More Info | KDM1A Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Shi, Y. et al. (2004) Cell 119, 941-953. 2. Wysocka, J. et al. (2006) Nature 442, 86-90. 3. Wysocka, J. et al. (2005) Cell 121, 859-872. 4. Jacobs, S.A. and Khorasanizadeh, S. (2002) Science 295, 2080-2083. 5. Nielsen, P.R. et al. (2002) Nature 416, 103-107. 6. Shi, Y.J. et al. (2005) Mol. Cell 19, 857-864. 7. Lee, M.G. et al. (2005) Nature 437, 432-435. 8. Metzger, E. et al. (2005) Nature 437, 436-439. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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