NDR1/2 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | NDR1/2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: NDR1/2 antibody detects endogenous levels of NDR1/2. Function: Negative regulator of MAP3K1/2 signaling. Converts MAP3K2 from its phosphorylated form to its non-phosphorylated form and inhibits autophosphorylation of MAP3K2.Subunit Structure: Homodimeric S100B binds two molecules of STK38 (PubMed:14661952). Interacts with MOB1 and MOB2 (PubMed:15067004, PubMed:15197186). Interacts with MAP3K1 and MAP3K2 (via the kinase catalytic domain) (PubMed:17906693). Forms a tripartite complex with MOBKL1B and STK3/MST2 (PubMed:18362890). Interacts with MICAL1; leading to inhibit the protein kinase activity by antagonizing activation by MST1/STK4 (By similarity).Post-translational Modifications: ISGylated. Phosphorylated by STK3/MS |
| Immunogen | Immunogen: A synthesized peptide derived from human NDR1/2 Subcellular Location: Nucleus Tissue Specificity: Ubiquitously expressed with highest levels observed in peripheral blood leukocytes. |
| Other Names | [NDR 1; NDR; Ndr Ser/Thr kinase-like protein; NDR1; NDR1 protein kinase; Nuclear Dbf2 related kinase 1; nuclear Dbf2-related 1; Nuclear Dbf2-related kinase 1; Nuclear Dbf2-related protein; Serine/threonine protein kinase 38; Serine/threonine-protein kinase 38; STK 38; STK38; STK38_HUMAN; KIAA0965; NDR2; NDR2 protein kinase; nuclear Dbf2 related 2; Nuclear Dbf2 related kinase 2; Nuclear Dbf2-related kinase 2; Serine/threonine protein kinase 38 like; Serine/threonine-protein kinase 38-like; ST38L_HUMAN; Stk38l] |
| Gene, Accession # | [NDR1/2], Gene ID: 11329, NCBI: NP_001292031.1, UniProt: Q15208 |
| Catalog # | MBS9603197 |
| Price | $240, $280 |
| Order / More Info | NDR1/2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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