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Antigenic Specificity | CD74 |
Clone | [2D1B11] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified. |
Immunogen | Immunogen: Purified recombinant fragment of human CD74 (AA: 1-106) expressed in E. Coli. |
Other Names | [II; DHLAG; HLADG; Ia-GAMMA] |
Gene, Accession # | [CD74], Gene ID: 972, NCBI: P04233.3, UniProt: P04233 |
Catalog # | MBS8539051 |
Price | $280 |
Order / More Info | CD74 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |