p63 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | p63 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit polyclonal to p63. The p53 tumor suppressor protein plays a major role in cellular response to DNA damage and other genomic aberrations. Activation of p53 can lead to either cell cycle arrest and DNA repair or apoptosis (1). In addition to p53, mammalian cells contain two p53 family members, p63 and p73, which are similar to p53 in both structure and function (2). While p63 can induce p53-responsive genes and apoptosis, mutation of p63 rarely results in tumors (2). Amplification of the p63 gene is frequently observed in squamous cell carcinomas of the lung, head and neck (2,3). The p63 gene contains an alternative transcription intiation site that yields a 40 kDa deltaNp63 lacking the transactivation domain, and alternative splicing |
| Immunogen | Immunogen: A synthetic -peptide of human p63 |
| Other Names | [TP63; p63; p63; TP63; AIS; B(p51A); B(p51B); EEC3; KET; LMS; NBP; OFC8; RHS; SHFM4; TP53CP; TP53L; TP73L; p40; p51; p53CP; p63; p73H; p73L], [TP63; TP63; AIS; KET; LMS; NBP; RHS; p40; p51; p63; EEC3; OFC8; p73H; p73L; SHFM4; TP53L; TP73L; p53CP; TP53CP; B(p51A); B(p51B); KET; P63; P73H; P73L; TP73L; p63; CUSP; TP63; p73L] |
| Gene, Accession # | Gene ID: 8626, NCBI: NP_001108450.1, UniProt: Q9H3D4 |
| Catalog # | MBS125652 |
| Price | $275, $430 |
| Order / More Info | p63 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Levine, A. J. et al. (1997) Cell 88, 323-331. 2. Waltermann, A. et al. (2003) Oncogene 22, 5686-5693. 3. Hibi, K. et al. (2000) Proc. Natl. Acad. Sci. USA 97, 5462-5467. 4. Yang, A. et al. (1999) Nature 398, 714-718. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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