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Antigenic Specificity | XRCC3 |
Clone | [10F1/6] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | purified |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The x-ray repair cross-complementing (XRCC) proteins are responsible for efficiently repairing and maintaining genetic stability following DNA base damage. These genes share sequence similarity with the yeast DNA repair protein Rad51. XRCC1 is a protein that facilitates the DNA base excision repair pathway by interacting with DNA ligase III and DNA polymerase to repair DNA single-strand breaks. XRCC2 and XRCC3 are both involved in maintaining chromosome stability during cell division. XRCC2 is required for efficient repair of DNA double-strand breaks by homologous recombination between sister chromatids, and XRCC3 interacts directly with Rad51 to cooperate with Rad51 during recombinational repair. XRCC4 is an accessory factor of DNA Ligase |
Immunogen | Immunogen: Recombinant full-length human XRCC3 protein |
Other Names | [CMM6; DNA repair protein XRCC3; RAD51 like; X ray repair complementing defective repair in Chinese hamster cells 3; X-ray repair cross-complementing protein 3; XRCC3] |
Gene, Accession # | [XRCC3], Gene ID: 7517, NCBI: NP_001093588.1, UniProt: O43542 |
Catalog # | MBS4381343 |
Price | $190, $340, $340 |
Order / More Info | XRCC3 Antibody from MYBIOSOURCE INC. |
Product Specific References | Tebbs, R.S., et al. 1995. Proc. Natl. Acad. Sci. USA 92: 6354-6358. |