CD31 (PECAM1) Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | CD31 (PECAM1) |
| Clone | polyclonal |
| Host Species | n/a |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.1 mg, 0.2 mg |
| Concentration | n/a |
| Applications | Western Blot (WB), IHC (Immunohistochemistry), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Platelet endothelial cell adhesion molecule (PECAM-1, CD31) is a 130 kD glycoprotein that is constitutively expressed by endothelial cells and by platelets, neutrophils, monocytes, and some T- lymphocytes. It is an integral transmembrane protein that belongs to the immunoglobulin superfamily and that mediates both homotypic and heterotypic cell adhesion. These functions have implicated CD31 in a variety of important biological processes including inflammation, angiogenesis and wound healing.In particular, CD31 has an important role in neutrophil and monocyte emigration across vascular endothelium, processes that can be inhibited, both in vitro and in vivo, with anti-CD31 antibodies. |
| Immunogen | Source: Polyclonal CD31 antibody was produced from sera of rabbits immunized with synthetic protein containing CD31 antigenic determinants. Purification: Serum IgG fraction was purified by Protein A affinity chromatography. Purity: >95%. Dilution: A quick spin of the vial followed by reconstitution in 0.01M PBS pH 7.4 or other diluents |
| Other Names | [Rabbit CD31 purified; pecam1; pecam-1; cd31; cd-31;; PAb], [PECAM1; PECAM-1] |
| Gene, Accession # | [CD31], Gene ID: 5175, NCBI: NP_000433.4, UniProt: P16284 |
| Catalog # | MBS551038 |
| Price | $280, $385 |
| Order / More Info | CD31 (PECAM1) Antibody from MYBIOSOURCE INC. |
| Product Specific References | • prognostic and predictive impact of expression of the angiogenic markers cd105 and CD31 expression in patients with high risk breast cancer (hrbc).Cancer Res., Dec 2009; 69: 2154. • cd38/CD31, the ccl3 and ccl4 chemokines, and cd49d/vascular cell adhesion molecule-1 are interchained by sequential events sustaining chronic lymphocytic leukemia cell survival.Cancer Res., May 2009; 69: 4001 - 4009. • circulating monocytes expressing CD31: implications for acute and chronic angiogenesis.Am. J. Pathol., May 2009; 174: 1972 - 1980. • il-7 sustains CD31 expression in human naive cd4 t cells and preferentially expands the CD31 subset in a pi3k-dependent manner.Blood, Mar 2009; 113: 2999 - 3007. • transcriptional profiling of CD31 cells isolated from murine embryonic stem cells.Genes Cells, Feb 2009; 14: 243 - 260. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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