Edit |   |
---|---|
Antigenic Specificity | Human CD257 (BAFF, Tall-1) |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1k |
Format | Protein A purified |
Size | 0.1 mL |
Concentration | 1ug/ul |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Antibody ANC10G1 binds to CD257(BAFF) in EIA and blocks binding of recombinant in Flow cytometry, and blocks binding of recombinant CD257(BAFF)-muCD8 to receptors on Raji cell surface in Flow cytometry. mAb name/Clone: ANC2H3Human CD257 (B cell activating factor, BAFF, TALL-1, Blys, THANK) and CD256 (APRIL, a proliferation inducing ligand) are both type II molecules belonging to the TNF superfamily (TNFSFL #13b and 13 respectively). They are expressed by non-B cells, and are down regulated by mitogenic stimulation(2). BAFF and APRIL bind to at least two receptors: CD267 (TACI, transmembrane activator and CAML-interactor) and CD269 (BCMA, B cell maturation antigen), both of which are restricted to B cells(3, 4). Ligation of thes |
Immunogen | Immunogen: Recombinant soluble human CD257 |
Other Names | n/a |
Gene, Accession # | [CD257] |
Catalog # | MBS4159608 |
Price | $540 |
Order / More Info | Human CD257 (BAFF, Tall-1) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |