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Antigenic Specificity | RUVBL1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Possesses single-stranded DNA-stimulated ATPase and ATP-dependent DNA helicase (3' to 5' ) activity; hexamerization is thought to be critical for ATP hydrolysis and adjacent subunits in the ring-like structure contribute to the ATPase activity.Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome-DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-214 of human RUVBL1 (NP 003698.1). |
Other Names | [RVB1; TIH1; ECP54; TIP49; ECP-54; INO80H; NMP238; PONTIN; TIP49A; NMP 238; Pontin52] |
Gene, Accession # | [RUVBL1], Gene ID: 8607, NCBI: NP_003698.1, UniProt: Q9Y265 |
Catalog # | MBS8549377 |
Price | $280 |
Order / More Info | RUVBL1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |