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Antigenic Specificity | CREB3L2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total CREB3L2 protein. Transcriptional activator which is processed and activated during endoplasmic reticulum stress late phase. Binds to the cAMP response element (CRE) and activates transcription through CRE. Regulates the transcription of unfolded protein response target genes, preventing accumulation of unfolded proteins in damaged neurons. Also regulates the expression of SEC23A, accelerating protein trafficking from the ER to the Golgi thereby playing a key role in chondrocyte differentiation and formation of epiphyseal cartilage By similarity.Storlazzi C.T., Hum. Mol. Genet. 12:2349-2358(2003).Ota T., Nat. Genet. 36:40-45(2004).Scherer S.W., Science 300:767-772(2003). |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human CREB3L2. |
Other Names | [cAMP-responsive element-binding protein 3-like protein 2; BBF2 human homolog on chromosome 7; Processed cAMP-responsive element-binding protein 3-like protein 2; CREB3L2; BBF2H7] |
Gene, Accession # | [CREB3L2], Gene ID: 64764, NCBI: NP_001240704.1, UniProt: Q70SY1 |
Catalog # | MBS9408846 |
Price | $200, $255 |
Order / More Info | CREB3L2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |