Edit |   |
Antigenic Specificity | MMP9 |
Clone | [S51-82] |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG2a |
Format | allophycocyanin (APC) conjugate |
Size | 0.1 mg |
Concentration | 1mg/mL |
Applications | Immunohistochemistry (IHC), Western Blot (WB), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Background Info: Detects ~92kDa and ~82kDa (pro and active forms) Scientific Background: MMP9, otherwise known as matrix metalloproteinase 9, is involved in the breakdown of extracellular matrix in normal physiological processes such as embryonic development, reproduction and tissue remodeling, as well as in disease processes like arthritis and metastasis (1). Among the family members, MMP-2, MMP-3, MMP-7 and MMP-9 have been characterized as important factors for normal tissue remodeling during embryonic development, wound healing, tumor invasion, angiogenesis, carcinogenesis and apoptosis (2-4). MMP activity correlates with cancer development (2). One mechanism of MMP regulation is transcriptional (5). Once synthesized, MMP exists as a lat |
Immunogen | n/a |
Other Names | [MMP-9; CLG4B; 82kDa matrix metalloproteinase-9; collagenease type 4 beta; GELB; Macrophage gelatinase; MANDP2; Type V collagenase; 92 kDa gelatinase; 92 kDa type IV collagenase; Gelatinase B; MMP9; Matrix metalloproteinase 9], [Mmp9; Mmp9; MMP-9; GELB] |
Gene, Accession # | Gene ID: 81687, NCBI: NP_112317.1, UniProt: P50282 |
Catalog # | MBS800193 |
Price | $435 |
Order / More Info | MMP9 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Hirose Y., et al. (2008) Am J Hum Genet. 82(5): 1122-1129. 2. Coussens L.M., et al. (2002) Science 295: 2387-2391. 3. Sternlicht M.D., et al. (1999) Cell 98: 137-146. 4. Vu T.H., et al. (1998) Cell 93: 411-422. 5. Nagase H., et al. (1990) Biochemistry 29: 5783-5789. |