MMP2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMMP2
Clone[1H1]
Host SpeciesMouse
Reactive Specieshuman, mouse, rat
IsotypeIgG
FormatProtein A purified
Size0.02 mL, 0.06 mL, 0.12 mL
Concentrationn/a
ApplicationsImmunohistochemistry-Paraffin (IHC-p)
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DescriptionUbiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. Also cleaves KISS at a Gly-Leu bond. Appears to have a role in myocardial cell death pathways. Contributes to myocardial oxidative stress by regulating the activity of GSK3beta. Cleaves GSK3beta in vitro.PEX, the C-terminal non-catalytic fragment of MMP2, posseses anti-angiogenic and anti-tumor properties and inhibits cell migration and cell adhesion to FGF2 and vitronectin. L
ImmunogenImmunogen: Synthetic Peptide of MMP2
Other Names[MMP2]
Gene, Accession #[MMP2], Gene ID: 4313, NCBI: NP_001121363.1, UniProt: P08253
Catalog #MBS2549010
Price$110, $150, $225
Order / More InfoMMP2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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