WDR5 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityWDR5
Clonepolyclonal
Host SpeciesMouse
Reactive Specieshuman
Isotypen/a
Formatunconjugated
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionWD-repeat protein 5 (WDR5, also designated BMP-2-induced gene 3 kb or BIG-3) belongs to the family of WD-40 repeat proteins, and is essential for vertebrate development, Hox gene activation and global H3K4 trimethylation. WDR5 is a conserved subunit of Trithorax (TRX) histone methyltransferase complexes that selectively binds to dimethylated Lys4 (K4me2) in Histone H3 to promote K4 trimethylation by TRX. It is expressed in osteoblasts, chondrocytes, osteocytes and marrow stromal cells. The WDR5 protein contains 7 WD-repeats, which may play a role in its function of accelerating osteoblast differentiation.
ImmunogenImmunogen: Purified recombinant fragment of human WDR5 expressed in E. Coli.
Other Names[SWD3; BIG-3; WDR5], [WDR5; WDR5; SWD3; BIG-3; CFAP89; BIG3]
Gene, Accession #[WDR5], Gene ID: 11091, NCBI: NP_060058.1, UniProt: P61964
Catalog #MBS850228
Price$280
Order / More InfoWDR5 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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