DIO3 - middle region Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | DIO3 - middle region |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The protein encoded by this intronless gene belongs to the iodothyronine deiodinase family. It catalyzes the inactivation of thyroid hormone by inner ring deiodination of the prohormone thyroxine (T4) and the bioactive hormone 3,3',5-triiodothyronine (T3) to inactive metabolites, 3,3',5'-triiodothyronine (RT3) and 3,3'-diiodothyronine (T2), respectively. This enzyme is highly expressed in the pregnant uterus, placenta, fetal and neonatal tissues, suggesting that it plays an essential role in the regulation of thyroid hormone inactivation during embryological development. This protein contains a selenocysteine (Sec) residue, which is essential for efficient enzyme activity. The selenocysteine is encoded by the UGA codon, |
| Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human DIO3 |
| Other Names | [thyroxine 5-deiodinase; Type III iodothyronine deiodinase; thyroxine 5-deiodinase; iodothyronine deiodinase 3; 5DIII; DIOIII; Type 3 DI; Type-III 5'-deiodinase] |
| Gene, Accession # | [DIO3], Gene ID: 1735, NCBI: NP_001353.4, UniProt: P55073 |
| Catalog # | MBS3220802 |
| Price | $335 |
| Order / More Info | DIO3 - middle region Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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