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Antigenic Specificity | GRK2 (Ab-86) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total ADRBK1protein. Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner.Benovic J.L., FEBS Lett. 283:122-126(1991).Chuang T.T., J. Biol. Chem. 267:6886-6892(1992).Penn R.B., J. Biol. Chem. 269:14924-14930(1994). |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from N-terminal of human ADRBK1. |
Other Names | [ADRBK1; adrenergic; beta; receptor kinase 1; ARBK1] |
Gene, Accession # | [GRK2], Gene ID: 156, NCBI: NP_001610.2, UniProt: P25098 |
Catalog # | MBS9402465 |
Price | $200, $255 |
Order / More Info | GRK2 (Ab-86) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |