GRK2 (Ab-86) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityGRK2 (Ab-86)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatimmunogen affinity purified
Size0.05 mL, 0.1 mL
Concentration1.0 mg/ml
ApplicationsWestern Blot (WB)
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DescriptionThe antibody detects endogenous levels of total ADRBK1protein. Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner.Benovic J.L., FEBS Lett. 283:122-126(1991).Chuang T.T., J. Biol. Chem. 267:6886-6892(1992).Penn R.B., J. Biol. Chem. 269:14924-14930(1994).
ImmunogenImmunogen Type: Peptide Immunogen Description: Synthesized peptide derived from N-terminal of human ADRBK1.
Other Names[ADRBK1; adrenergic; beta; receptor kinase 1; ARBK1]
Gene, Accession #[GRK2], Gene ID: 156, NCBI: NP_001610.2, UniProt: P25098
Catalog #MBS9402465
Price$200, $255
Order / More InfoGRK2 (Ab-86) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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