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Antigenic Specificity | IRAK2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Anti-IRAK2 has no cross response to IRAK. Anti-IRAK2 will also recognize human IRAK2. IRAK2 Antibody: The pro-inflammatory cytokine IL-1 induces cellular response through two subunits of its receptor, IL-1 receptor I (IL-1RI) and IL-1 receptor accessory protein (IL-1RAcP). IL-1 receptor-associated kinase (IRAK) mediates activation of NF-κB, which is a pivotal transcription factor mediating inflammatory and immune response. A novel member in the IRAK/Pelle family has been identified and designated IRAK2. Both IRAK and IRAK2 recruit to the subunits of the IL-1R complex after IL-1 binding and lead to NF-κB activation. IRAKs also associate with Toll like receptor (TLR) and the dominant negative mutants of IRAKs inhibit LP |
Immunogen | Immunogen: IRAK2 antibody was raised against a peptide corresponding to 17 amino acids near the carboxy terminus of mouse IRAK2a which is common to all four isoforms. Buffer: IRAK2 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [IRAK2; IRAK-2; AI649099; 6330415L08Rik; Interleukin-1 receptor-associated kinase-like 2; IRAK-2; interleukin-1 receptor-associated kinase 2], [Irak2; Irak2; IRAK-2; AI649099; 6330415L08Rik; IRAK-2; mu-IRAK-2] |
Gene, Accession # | [Irak2], Gene ID: 108960, NCBI: AAO24761, UniProt: Q8CFA1 |
Catalog # | MBS150516 |
Price | $375 |
Order / More Info | IRAK2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |