IRAK2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityIRAK2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatpeptide affinity purified
Size0.1 mg
Concentration1 mg/mL
ApplicationsELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
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DescriptionSpecificity: Anti-IRAK2 has no cross response to IRAK. Anti-IRAK2 will also recognize human IRAK2. IRAK2 Antibody: The pro-inflammatory cytokine IL-1 induces cellular response through two subunits of its receptor, IL-1 receptor I (IL-1RI) and IL-1 receptor accessory protein (IL-1RAcP). IL-1 receptor-associated kinase (IRAK) mediates activation of NF-κB, which is a pivotal transcription factor mediating inflammatory and immune response. A novel member in the IRAK/Pelle family has been identified and designated IRAK2. Both IRAK and IRAK2 recruit to the subunits of the IL-1R complex after IL-1 binding and lead to NF-κB activation. IRAKs also associate with Toll like receptor (TLR) and the dominant negative mutants of IRAKs inhibit LP
ImmunogenImmunogen: IRAK2 antibody was raised against a peptide corresponding to 17 amino acids near the carboxy terminus of mouse IRAK2a which is common to all four isoforms. Buffer: IRAK2 Antibody is supplied in PBS containing 0.02% sodium azide.
Other Names[IRAK2; IRAK-2; AI649099; 6330415L08Rik; Interleukin-1 receptor-associated kinase-like 2; IRAK-2; interleukin-1 receptor-associated kinase 2], [Irak2; Irak2; IRAK-2; AI649099; 6330415L08Rik; IRAK-2; mu-IRAK-2]
Gene, Accession #[Irak2], Gene ID: 108960, NCBI: AAO24761, UniProt: Q8CFA1
Catalog #MBS150516
Price$375
Order / More InfoIRAK2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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