Phospho-Gab1 (Tyr307) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Phospho-Gab1 (Tyr307) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Phospho-Gab1 (Tyr307) antibody detects endogenous levels of Gab1. Function: Adapter protein that plays a role in intracellular signaling cascades triggered by activated receptor-type kinases. Plays a role in FGFR1 signaling. Probably involved in signaling by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR).Subunit Structure: Interacts with GRB2 and with other SH2-containing proteins. Interacts with phosphorylated LAT2. Interacts with PTPRJ. Identified in a complex containing FRS2, GRB2, GAB1, PIK3R1 and SOS1. Interacts (phosphorylated) with PTPN11. Interacts with HCK.Post-translational Modifications: Phosphorylated in response to FGFR1 activation. Phosphorylated on tyrosine residue(s) by the e |
| Immunogen | Immunogen: A synthesized peptide derived from human Gab1 around the phosphorylation site of Tyr307. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken Similarity: Pig (92%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (92%), Dog (100%), Chicken (92%) |
| Other Names | [Gab 1; GAB1; GAB1_HUMAN; GRB 2 associated binder 1; GRB 2 associated binding protein 1; GRB2 associated binding protein 1 isoform a; GRB2 associated binding protein 1 isoform b; GRB2-associated binder 1; GRB2-associated-binding protein 1; Growth factor receptor bound protein 2-associated protein 1] |
| Gene, Accession # | [Gab1], Gene ID: 2549, NCBI: NP_002030.2, UniProt: Q13480 |
| Catalog # | MBS9600673 |
| Price | $240, $280 |
| Order / More Info | Phospho-Gab1 (Tyr307) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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