Edit |   |
Antigenic Specificity | PPP3CC (C-term), 482-512 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This PPP3CC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 482-512 amino acids from the C-terminal region of human PPP3CC. Calmodulin-dependent protein phosphatase, calcineurin, is involved in a wide range of biologic activities, acting as a Ca(2+)-dependent modifier of phosphorylation status. In testis, the motility of the sperm is thought to be controlled by cAMP-dependent phosphorylation and a unique form of calcineurin appears to be associated with the flagellum. The calcineurin holoenzyme is composed of catalytic and regulatory subunits of 60 and 18 kD, respectively. At least 3 genes, calcineurin A-alpha, calcineurin A-beta, and calcineurin A-gamma, have been cloned for the catalytic subuni |
Immunogen | n/a |
Other Names | [Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform; CAM-PRP catalytic subunit; Calcineurin; testis-specific catalytic subunit; Calmodulin-dependent calcineurin A subunit gamma isoform; PPP3CC; CALNA3; CNA3] |
Gene, Accession # | [PPP3CC], Gene ID: 5533, NCBI: NP_001230903.1, UniProt: P48454 |
Catalog # | MBS9201458 |
Price | $165, $370 |
Order / More Info | PPP3CC (C-term), 482-512 Antibody from MYBIOSOURCE INC. |
Product Specific References | Eastwood, S.L., et al., Biol. Psychiatry 57(7):702-710 (2005). Gerber, D.J., et al., Proc. Natl. Acad. Sci. U.S.A. 100(15):8993-8998 (2003). Bennasser, Y., et al., Virology 303(1):174-180 (2002). Esau, C., et al., J. Exp. Med. 194(10):1449-1459 (2001). Muramatsu, T., et al., Biochem. Biophys. Res. Commun. 188(1):265-271 (1992). |