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Antigenic Specificity | Mouse CD64 |
Clone | [AT152-9] |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2a |
Format | unconjugated |
Size | 0.25 mg |
Concentration | IgG concentration 1.0 mg/ml |
Applications | Immunohistochemistry (IHC) Formalin, Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rat anti mouse CD64 antibody, clone AT152-9, recognizes mouse CD64 also known as FcRI. CD64 is a high affinity activatory receptor for IgG2a and a low affinity receptor for IgG2b and IgG3 type antibodies. The interaction between Fc receptors and antibodies play important roles in both the innate and adaptive immune responses. CD64, through binding of the Fc segment of IgG, mediates phagocytosis and plays a role in antibody-dependent cellular cytotoxicity and clearance of immune complexes. In addition, CD64 also functions as an antigen capture for presentation to T-cells and also mediates the release of cytokines and reactive oxygen intermediates including interleukin (IL)-1, IL-6 and tumor necrosis factor (TNF) alpha. It is constitutively e |
Immunogen | Immunogen: HEK293F cells expressing CD64 and gamma chain Fusion Partners: Spleen cells from immunised rats were fused with cells of the NS-1 myeloma cell line |
Other Names | [FcRI, Fcg1], [Fcgr1; Fcgr1; CD64; IGGHAFC; AI323638; AV092959; FcgammaRI; Fcg1; IgG Fc receptor I; FcRI] |
Gene, Accession # | [CD64], Gene ID: 14129, NCBI: P26151.1, UniProt: P26151 |
Catalog # | MBS224780 |
Price | $430 |
Order / More Info | Mouse CD64 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |