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Antigenic Specificity | Rhodopsin |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human, bovine, mouse, porcine and rat |
Isotype | IgG1 |
Format | affinity purified |
Size | 0.1 mL |
Concentration | 100ug/100ul |
Applications | Immunofluorescence (IF), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | n/a |
Immunogen | Immunogen: Rhodopsin is the protein in the mammalian retina responsible for the light sensitivity of rod cells, which are responsible for vision in low light levels. Somewhat surprisingly, the rhodopsin protein turned out to be a typical member of the seven transmembrane G protein-coupled receptor (GPCR) superfamily. Whereas other GPCRs initiate signaling on binding a specific ligand, rhodopsin exists with a ligand already bound, specifically the vitamin A related substance retinal. Retinal can |
Other Names | [Rhodopsin], [RHO; RHO; RP4; OPN2; CSNBAD1; OPN2] |
Gene, Accession # | Gene ID: 6010, NCBI: NP_000530.1, UniProt: P08100 |
Catalog # | MBS415058 |
Price | $370 |
Order / More Info | Rhodopsin Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Molday RS. Photoreceptor membrane proteins, phototransduction, and retinal degenerative disease. The Frienwald lecture. Invest Ophthalmol Vis Sci. 39:2491-513 (1998).2. Yau,KW. Phototransduction Mechanism in Retinal Rods and Cones. The Frienwald lecture. Invest Ophthalmol Vis Sci. 35:9-32 (1994).3. Wilden U, Hall SW, Kohn H. Phosphodiesterase activation by photoexcited rhodopsin is quenched when rhodopsin is phosphorylated and binds the intrinsic 48-kDa protein of rod outer segments. Proc Natl Acad Sci USA 83:1174-8 (1986).4. Smith WC, Mc Dowell JH, Dugger DR, Miller R, Arendt A, Popp MP, Hargrave PA. Identification of regions of arrestin that bind to rhodopsin. Biochemistry Mar 38:2752-61 (1999). |