CD62E (E-selectin, ELAM-1) Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | CD62E (E-selectin, ELAM-1) |
| Clone | polyclonal |
| Host Species | n/a |
| Reactive Species | mouse, human, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunocytochemistry (ICC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to a region of N-terminal residues of CD62E. CD62E, known as E-selectin, is a cell adhesion molecule expressed only on endothelial cells activated by cytokines. Like other selectins, it plays an important part in inflammation. During inflammation, E-selectin plays an important part in recruiting leukocytes to the site of injury. The main ligands recognised by CD62E are oligosaccharides related to sialyl lewis x. P-selectin has a similar function, but is expressed on the endothelial cell surface within minutes as it is stored within the cell rather than produced on demand. |
| Immunogen | n/a |
| Other Names | [E-selectin; ELAM-1], [SELE; SELE; ELAM; ESEL; CD62E; ELAM1; LECAM2; ELAM1; ELAM-1; LECAM2] |
| Gene, Accession # | [CD62E], Gene ID: 6401, NCBI: NP_000441.2, UniProt: P16581 |
| Catalog # | MBS857112 |
| Price | $280 |
| Order / More Info | CD62E (E-selectin, ELAM-1) Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Phillips M.L., Nudelman E., et al: ELAM-1.mediates cell adhesion by recognition of a carbohydrate ligand, sialyl-Lex.; Science 2.0:1.3.-1.3.1.90). 2. Mills A.; Modelling the carbohydrate recognition domain of human E-selectin.; FEBS Lett. 3.:5-1.(1.93.) Collins T., Williams A., Johnston G.I., et al; Structure and chromosomal location of the gene for endothelial-leukocyte adhesion molecule 1.; J. Biol. Chem. 2.6:2.66-2.73.1.91. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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