CD14 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CD14 |
| Clone | [AT87H7] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2b, k |
| Format | Protein A purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | 1 mg/ml |
| Applications | ELISA (EIA), Western Blot (WB), Flow Cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The protein encoded by this gene is a component of the innate immune system. CD14 exists in two forms, one anchored to the membrane by a glycosylphosphatidylinositol tail (mCD14), the other a soluble form (sCD14). Soluble CD14 either appears after shedding of mCD14 (48kDa) or is directly secreted from intracellular vesicles (56kDa).The x-ray crystal structure of human CD14 reveals a monomeric, bent solenoid structure containing a hydrophobic amino-terminal pocket. CD14 was the first described pattern recognition receptor. CD14 acts as a co-receptor (along with the Toll-like receptor TLR4 and MD-2) for the detection of bacterial lipopolysaccharide (LPS). CD14 can bind LPS only in the presence of lipopolysaccharide-binding protein (LBP). Alth |
| Immunogen | Immunogen: Recombinant human CD14 (20-349aa) purified from E Coli. |
| Other Names | [monocyte differentiation antigen CD14; Myeloid cell-specific leucine-rich glycoprotein], [CD14; CD14] |
| Gene, Accession # | [CD14], Gene ID: 929, NCBI: NP_001167576, UniProt: P08571 |
| Catalog # | MBS200345 |
| Price | $240, $315 |
| Order / More Info | CD14 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Kirkland T.N., et al. (1998) Prog Clin Biol Res. 397: 79-87; Kelley S.L., et al. (2013) Journal of Immunology. 190 (3): 1304-1311.; Kitchens R.L., et al. (2000) Chem Immunol Chemical Immunology and Allergy. 74: 61-82; Tapping R.I., et al. (2000) Chem Immunol Chemical Immunology and Allergy. 74: 108-121 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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