TNFRSF14 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTNFRSF14
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL
Concentrationn/a
ApplicationsELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC)
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DescriptionTumor necrosis factor receptor (TNFR) superfamily members are defined by cysteine-rich domains in their extracellular regions that bind TNF-related ligands that share a common structural homology in their extracellular domain. TNFRSF14 was initially identified as the Herpesvirus entry mediator and upon binding to the herpes simplex virus (HSV) envelope glycoprotein D or either of its natural ligands LIGHT and lymphotoxin alpha (LT), activates the transcription factors NF-kB and AP-1. Activation of this signal transduction pathway in T cells stimulates T cell proliferation and cytokine production, leading to inflammation and enhanced CTL-mediated tumor immunity, suggesting that these proteins may be useful as potential targets for controllin
ImmunogenImmunogen Type: Peptide Immunogen Description: Raised against a 16 amino acid peptide from near the carboxy terminus of human TNFRSF14.
Other Names[Tumor necrosis factor receptor superfamily 14, Herpesvirus entry mediator, HVEM, TR2]
Gene, Accession #[TNFRSF14], Gene ID: 8764, NCBI: NP_003811.2, UniProt: Q92956
Catalog #MBS9401141
Price$320
Order / More InfoTNFRSF14 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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