Edit |   |
---|---|
Antigenic Specificity | CD73 / NT5E (CT) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | Ig fraction |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Polyclonal Antibody to detect CD73 in human and mouse samples. Background: CD73 (also designated ecto-5'-nucleotidase, E5NT, NT, NT5, NTE, eN and eNT) is a glycosyl-phosphatidylinositol (GPI)-anchored adhesion protein that catalyzes the dephosphorylation of extracellular purine and pyrimidine nucleotides to their corresponding bioactive nucleosides. CD73 is a dimer of two identical subunits that depends on GPI to link with the external face of the plasma membrane. Similar to other GPI-anchored proteins, CD73 mediates co-stimulatory signals in T cell activation. CD73 has few structural variants, yet elicits diverse biological function through differential regulation in endothelial cells (EC), subpopulations of B and T cells, germinal center |
Immunogen | Immunogen: This CD73 (NT5E) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 520-550 amino acids from the C-terminal region of human CD73 (NT5E). Positive Control: Western blot: mouse brain tissue lysate, NT5E 293 ceel lysate. IHC: human placenta tissue. |
Other Names | [NT5E; NT5; NTE; 5'-nucleotidase; Ecto-5'-nucleotidase], [NT5E; NT5E; NT; eN; NT5; NTE; eNT; CD73; E5NT; CALJA; NT5; NTE; 5'-NT] |
Gene, Accession # | [CD73/NT5E], Gene ID: 4907, NCBI: NP_001191742.1, UniProt: P21589 |
Catalog # | MBS840499 |
Price | $290 |
Order / More Info | CD73 / NT5E (CT) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |