5-HT-2A Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | 5-HT-2A |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: 5-HT-2A antibody detects endogenous levels of total 5-HT-2A. Function: G-protein coupled receptor for 5-hydroxytryptamine (serotonin) (PubMed:1330647, PubMed:18703043, PubMed:19057895). Also functions as a receptor for various drugs and psychoactive substances, including mescaline, psilocybin, 1-(2, 5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD) (PubMed:28129538). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors (PubMed:28129538). Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways (PubMed:28129538). Sig |
| Immunogen | Immunogen: A synthesized peptide derived from human 5-HT-2A Subcellular Location: Cell Membrane. Localizes to the post-synaptic thickening of axo-dendritic synapses. Tissue Specificity: Detected in brain cortex (at protein level). Detected in blood platelets. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog Similarity: Pig (100%), Bovine (90%), Horse (100%), Sheep (90%), Rabbit (100%), Dog (100%) |
| Other Names | [5 HT 2; 5 HT 2A; 5 HT2 receptor; 5 HT2A; 5 hydroxytryptamine receptor 2A; 5-HT-2; 5-HT-2A; 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled; 5-hydroxytryptamine 2A receptor; 5-hydroxytryptamine receptor 2A; 5HT2A_HUMAN; HTR 2; HTR 2A; HTR2; HTR2, formerly; HTR2A; serotonin 5-HT-2 receptor, formerly; serotonin 5-HT-2A receptor; Serotonin receptor 2A] |
| Gene, Accession # | [5-HT-2A], Gene ID: 3356, NCBI: NP_000612.1, UniProt: P28223 |
| Catalog # | MBS9609217 |
| Price | $240, $280 |
| Order / More Info | 5-HT-2A Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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