AKT1 (N-term), 115-144 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityAKT1 (N-term), 115-144
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman (predicted reactivity: bovine, mouse)
Isotypen/a
Formatpurified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.5
ApplicationsELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB), Immunofluorescence (IF), Flow Cytometry (FC/FACS)
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DescriptionThis AKT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 115-144 amino acids from the N-terminal region of human AKT1. The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent
Immunogenn/a
Other Names[RAC-alpha serine/threonine-protein kinase; Protein kinase B; PKB; Protein kinase B alpha; PKB alpha; Proto-oncogene c-Akt; RAC-PK-alpha; AKT1; PKB; RAC]
Gene, Accession #[AKT1], Gene ID: 207, NCBI: NP_001014431.1, UniProt: P31749
Catalog #MBS9202930
Price$165, $370
Order / More InfoAKT1 (N-term), 115-144 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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