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Antigenic Specificity | CD18 |
Clone | [10E12] |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG2b |
Format | ascites |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD18, also known as ITGB2 (integrin beta chain beta 2). Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. CD18 is expressed by most leucocytes. Defects in this gene are the cause of leukocyte adhesion deficiency type I (LAD1). Two transcript variants encoding the same protein have been identified for this gene. |
Immunogen | Immunogen: Purified recombinant fragment of CD18 expressed in E. Coli. |
Other Names | [LAD; MF17; LCAMB; LFA-1; ITGB2] |
Gene, Accession # | [CD18], NCBI: NP_000202.2, UniProt: P05107 |
Catalog # | MBS8538530 |
Price | $280 |
Order / More Info | CD18 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |