Edit |   |
---|---|
Antigenic Specificity | HCFC1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total HCFC1 protein. Involved in control of the cell cycle. Also antagonizes transactivation by ZBTB17 and GABP2; represses ZBTB17 activation of the p15(INK4b) promoter and inhibits its ability to recruit p300. Coactivator for EGR2 and GABP2. Tethers the chromatin modifying Set1/Ash2 histone H3 'Lys-4' methyltransferase (H3K4me) and Sin3 histone deacetylase (HDAC) complexes (involved in the activation and repression of transcription, respectively) together. Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. In case o |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from N-terminal of human HCFC1. |
Other Names | [TF3C-gamma; TF3C3; TFIIIC 102 kDa subunit; TFIIIC102; TFIIICgamma] |
Gene, Accession # | [HCFC1], Gene ID: 3054, NCBI: NP_005325.2, UniProt: P51610 |
Catalog # | MBS9402063 |
Price | $200, $255 |
Order / More Info | HCFC1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |