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Antigenic Specificity | Ogg1 Picoband |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: 8-Oxoguanine glycosylase also known as OGG1 is a DNA glycosylase enzyme that, in humans, is encoded by theOGG1 gene. This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial loca |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence of human Ogg1 (KYFQLDVTLAQLYHHWGSVDSHFQEVAQKFQGVRLLRQD). Subcellular Localization: Nucleus, nucleoplasm. Tissue Specificity: Ubiquitous. |
Other Names | [N-glycosylase/DNA lyase; 8-oxoguanine DNA glycosylase; DNA-(apurinic or apyrimidinic site) lyase; AP lyase; OGG1; MMH; MUTM; OGH1] |
Gene, Accession # | [Ogg1], Gene ID: 4968, NCBI: NP_002533.1, UniProt: O15527 |
Catalog # | MBS1750482 |
Price | $280 |
Order / More Info | Ogg1 Picoband Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |